Saturday 14 October 2017

Dr. Mercola: Vitamin B12 Nighttime Wakefulness and Daytime Sleepiness? Give These 3 Nutrients a Try

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"You May Sleep Better at Night by Taking Vitamin B12 During the Day…*"

As you age, it becomes more difficult to get a good night's sleep because your body becomes less efficient at making this vitamin - taking this can help fix the problem while also boosting your energy, improving your mood and memory...*

Many experts previously believed that strict vegetarians were the primary group that could develop a vitamin B12 deficiency. If you had adequate stores of this important nutrient in your body, the experts believed you were “safe” for many years from developing a B12 deficiency.

Now we know better.

Vitamin B12 deficiency and depletion are much more common than previously thought, especially in the over-60 population. In fact, it's believed that almost one in four people over 60 have deficient levels of this vital vitamin.

Equally disturbing are emerging signs that other age groups harbor suboptimal blood levels of B12 as well.

Why is vitamin B12 deficiency such a big deal?

Your body depends on vitamin B12 for a host of functions, including…

    Helping to maintain normal energy levels*
    Promoting healthy neurological activity, including mental alertness*
    Supporting normal homocysteine levels for healthy cardiac function*
    Helping to ease occasional stress and sleeplessness*
    Maintaining healthy cell growth and repair*
    Promoting normal immune function*
    Supporting normal metabolism of carbohydrates and fats*

When your blood levels of vitamin B12 are low, one or more of these functions may be disrupted.*

Without adequate blood levels of B12, you can experience symptoms related to low energy, mental fatigue, mood changes, sleep difficulties, and even occasional indigestion.*

Your body relies on the efficient conversion of carbohydrates to glucose – your body's source of fuel – just like your car needs to be able to use gas to run smoothly. Vitamin B12 plays a major role in that conversion in your body.* Likewise, B12 enables your body to convert fatty acids into energy as well.*

Contrary to what you might have heard, there's really no solid evidence that supplemental vitamin B12 helps you lose weight.

Overall, vitamin B12 is a nutrient your body cannot do without for efficient, healthy metabolism of fats and carbohydrates.*
How You Get Vitamin B12 Deficient

The older you get the more likely you are to have a vitamin B12 deficiency. The two ways that you become deficient in vitamin B12 are from not getting enough in your diet and from losing the ability to absorb it.

I recently visited India which is primarily a vegetarian based culture and current studies there show about 80% of the adults are deficient in vitamin B12. However, vegans are not the only ones who can become vitamin B12 deficient.

The older you get the more your digestive system breaks down, especially if you have been following the standard American diet. Specifically the lining of your stomach gradually loses its ability to produce hydrochloric acid which releases vitamin B12 from your food. The use of antacids or anti-ulcer drugs will also lower your stomach acid secretion and decrease your ability to absorb vitamin B12. Infection with Helicobactor pylori, a common contributor to stomach ulcers, can also result in vitamin B12 deficiency.

However the main cause of vitamin B12 deficiency is a term researchers call food-cobalamin malabsorption syndrome. Cobalamin is the scientific term for vitamin B12. This typically results when your stomach lining loses its ability to produce intrinsic factor which is a protein that binds to vitamin B12 and allows your body to absorb it at the end of your small intestine.
Vitamin B12 Deficiency Figure

Figure 1. Cobalamin (cbl) absorption and metabolic pathway. (A) Structure of cobalamin (vitamin B12) with a corrin ring bound to a central cobalt atom. (B) The metabolic journey of cbl from nutrient intake to its intestinal absorption. Endocytic receptors and proteins responsible for vitamin B12 intestinal absorption include cubilin (CUBN), amnionless (AMN), receptor-associated protein (RAP) and megalin (LRP-2). The membrane megalin/transcobalamin II (TCII) receptor complex allows the cellular uptake of cbl. Lysosomal-mediated degradation of TCII and subsequent release of free cbl is essential for vitamin B12 metabolic functions. MS: methonine synthase; THF: tetrahydrofolate; MTHFR: methyltetrahydrofolate reductase; MCM: methylmalonyl coA mutase.
NEW Form of Vitamin B12 Not Found in Most Health
Food and Vitamin Stores

If you often feel tired, run-down, and lacking in energy, you're not alone. Low energy is one of our country's biggest health complaints.

Some of the top reasons for this are:

    Refined foods sold in grocery stores are depleted of vital nutrients...
    Refined foods are loaded with sugar...
    Refined foods are full of chemicals...
    Refined foods are overloaded with food colorings; and...
    Refined foods are loaded with preservatives...

...but it doesn't stop there, either.

Add the harmful effects of caffeine, pollution, conventional therapies, and the stress most of us experience every day... and you've got yourself a recipe for energy drain.

Well, I'm here to tell you there's a new way to give yourself extra energy.* Actually, a cutting edge way to feel more energized -- without the jitteriness of caffeine.* More on this in a moment.

Now, of course, powering up with extra energy is just one of B12's many health benefits.* But you need to...
Make Sure Your Vitamin B12 Is Made from This...

Otherwise, you could be wasting your time. How could that be?

Well, the answer simply put is… not all types of B12 (cobalamins) are created equal.

There are generally three main types of cobalamins used in B12 supplements…

    Hydroxycobalamin
    Cyanocobalamin
    Methylcobalamin

Even though cyanocobalamin B12 is probably the most popular form of B12 in supplements, I don't believe it's the most effective. That distinction goes to methycobalamin (methyl B12).

And methyl B12 is the cobalamin compound of choice in B12 Energy Booster* because…

    Studies suggest that methyl B12 may be better utilized and retained in the body.*
    Methyl B12 is the active form of vitamin B12 and evidence indicates it has some applications not shared by other forms of vitamin B12.*
    With other forms of B12, your body must convert them into a coenzyme form for you to benefit. Not so with methyl B12… it's already in the active coenzyme form naturally in your body.*

What Critical Health Benefits Does this Vitamin Bring to the Table?

For starters, vitamin B12 helps folic acid regulate the formation of red blood cells, and helps your body use iron.*

In addition, it is also needed for proper digestion, food absorption, carbohydrate and fat metabolism.* It also helps keep your nervous system healthy by assisting the nerves of your body to function and communicate in an optimal manner.* 

But that's not all... far from it!

B12 also helps in cell formation and cellular longevity.* Plus, it can support female reproductive health, and promote normal nerve growth and development by maintaining the fatty sheaths.* These fatty sheaths play a vital role as they cover and protect your nerve endings.*

What's more, this workhorse of a micronutrient is critical to your circulation and adrenal hormone production -- plus, it helps boost your immunity.* And, oh yes, let's not forget...

Vitamin B12 supports a healthy mood and feelings of well-being.* And then there's this -- it also provides excellent support for your memory, mental clarity, and concentration.*

Aside from using B12 to give you an energy boost, when does it also make sense to supplement with this all-important vitamin? Well, there are several good reasons to take vitamin B12.

And the first reason to take it is if you are a carb type or a strict vegetarian.
If You Avoid Meat, You Probably Need to Take B12
Vegetarian Increased Need for Vitamin B12
Vegetarians have an increased need for vitamin B12

Many people avoid red meats for a large variety of reasons. If you are one of them, you are at a high risk for developing vitamin B12 deficiency. Why? Because plant sources have virtually no vitamin B12. And oral forms of B12 in nearly all supplements are practically useless, as little is absorbed into your bloodstream.

Vegetarians should take this essential micronutrient to ensure an adequate supply of it, because it is found almost exclusively in animal tissues. And, the few plant foods that are sources of B12 are actually B12 analogs -- not the form that provides all the benefits of the real deal.

Simply put, an analog is a substance that blocks the uptake of true B12. The result being, your body's need for the nutrient actually increases.

Furthermore, your body's need for this nutrient may also increase if you take Metformin©. Metformin may interfere with calcium metabolism. And this interference may reduce B12 absorption, because this absorption requires calcium.

Studies suggest that 10% to 30% of patients taking Metformin show evidence of reduced vitamin B12 absorption. That's why it is important to speak with your doctor to discuss the best way to maintain B12 levels when taking this medication.

Now, if getting a good night's sleep has also become increasingly more difficult for you, here's...
What Your Sleeping Difficulties May Be Trying to Tell You!

If you suffer from sleeping difficulties, I recommend taking vitamin B12 during the day. I believe it can help you.* Here's why.

B12 plays a vital role in melatonin production.* Melatonin has been called "the sleep hormone" because it is responsible for letting you get a good night's sleep. 

As you age, it becomes increasingly more difficult to get a good night's sleep because your body becomes less efficient at making this hormone. And that's why it's a good idea to take B12 to help you sleep like a baby each night.*

Moreover, a vitamin B12 deficiency can have other annoying consequences too.
Do You or a Loved One Experience Any of the Following?

Not many know it, but if you or a family member experience:

    Tiredness and feelings of weakness...*
    Less-than-optimal nervous system functioning...*
    Less-than-optimal eye health...*
    Loss of appetite and unintended weight loss...*
    Occasional constipation and gas...*
    Feelings of mild moodiness...*
    Less-than-optimal memory...*
    A tendency toward nervousness...*
    Less-than-optimal balance...*
    Less-than-optimal liver or heart health...*
    Premature grey hair...*
    Occasional digestive issues...*

...you may need to supplement with vitamin B12, even if you eat foods rich in B12. Oddly enough, that wasn't a typo.

You can eat plenty of meat, poultry, lamb's liver, brewer's yeast, clams, eggs, herring, mackerel, kidneys, milk, dairy products, or seafood -- and still have low levels of B12. How can that be?

It could be because your body is unable to absorb it from your gut. You see B12 needs the help of a protein in order to be absorbed. That protein is called intrinsic factor. And because the lining of your stomach makes intrinsic factor, people with less-than-optimal gastrointestinal health often need to supplement with B12.*

Likewise, most people over the age of 50 have a limited ability to absorb B12, too. Thus, the need for supplementation.
Pain-Free Supplementation
Vitamin B12 Spray

With that said, the form of vitamin B12 I'm recommending does NOT come as a pill, tablet, capsule, gelcap, or liquid.

Amazingly, it's B12 in a spray.

A modern marvel that I believe gives most people far better results than anything else. The name of this new product is B12 Energy Booster.* And it's only available here on Mercola.com.

Now, here's the question you may be asking at this point:
How Can Something as Simple as a Spray
Work so Much Better Than a Pill, Tablet, or Capsule?

Quite simply, the B12 in B12 Energy Booster* comes in an easily absorbed form your body can now use.*

It turns out that this fine-mist spray formula you spray into your mouth causes the essential nutrients to become absorbed rapidly.*

As a result, it delivers more of this product's nutrients to your circulatory system, tissues, and cells quickly.*

Remember -- only a small fraction of this crucial vitamin gets absorbed through your gut when you take it in a pill, tablet, capsule, or gelcap.

And to make B12 Energy Booster* even more effective, I made sure our manufacturer used this.
Here's the REAL TRUTH about the B12 in Most Multivitamins:

It all boils down to this...

Most of them contain 100-200 micrograms of B12. But, if you actually took 500 micrograms of B12, you'd get an absorption of about 1.8 micrograms. Let me repeat, only 1.8 out of a total of 500 micrograms. That's an absorption rate of only one third of one percent! But, that's only half of the story.

The late Victor Herbert, a renowned B12 researcher, said that many multivitamin products on the market today contain dangerous B12 analogs.

In other words, analogs get created when crystalline B12 interacts with other nutrients in multivitamin products, such as vitamin C, iron and copper -- increasing your body's need for B12. Does the company selling the multivitamin tell you this vital bit of information? Probably not!     

Truth be told, most multi-vitamins sold today are a complete waste of money when it comes to their B12 quality and performance. Now listen up:

Each bottle of B12 Energy Booster* delivers a serving size (1,000 micrograms) of 6 sprays per day. And you get approximately 205 metered sprays in each container. Because this ends up being a 32-day supply, you actually receive a nice bonus of 4 additional days!

How can you beat that? And that's just the beginning. Another nice feature of B12 Energy Booster* is that it...
Comes in a Tasty Natural Blackberry Flavor

And in addition to tasting great, it's absolutely FREE of...

    Sugar
    Yeast
    Starch
    Wheat
    Soy
    Gluten
    Eggs
    Salt
    Dairy

Better yet, it's also FREE of artificial flavors, color, synthetics, binders, fillers, wax, shellac, talcum, and animal gelatin.

The bottom line is that our B12 Energy Booster* is stimulant-free, contains only natural ingredients, and tastes great! Best of all, it's packaged in a convenient pre-metered, non-aerosol container that easily fits in your purse or pocket. Last but not least, it...
Costs Far Less Than a Cup of Even "Economy" Coffee

By now, you're probably wondering how much B12 Energy Booster* costs. I'm happy to tell you the price is very reasonable.

You can get a full 32-day supply for only $16.97 -- an excellent value when you consider all the health-promoting and energy-boosting benefits you get.* That's just 50 cents a day -- far less than that cup of caffeine-loaded coffee (and you know that caffeine is certainly not a smart solution to give you more energy).

Why am I being so generous?

Because I know how much you can benefit from this breakthrough product, and I want to give you every incentive to get started right away. And whether you order one, two, three or more B12 Energy Booster* for yourself and loved ones, you're completely protected by my...
100% Unconditional Guarantee

No doubt about it, B12 Energy Booster* is an exceptional product. After all, it can help crank up your energy, and improve overall health and well-being...*

In fact, I'm so sure you'll be delighted with it that I'm offering the following unconditional guarantee.

If you're unsatisfied with B12 Energy Booster* for any reason at all, simply let me know anytime. Yes, you read that right. Anytime. I am so confident that you will be more than satisfied with your purchase of my Vitamin B12 Energy Booster* Spray, I am providing you a 100% Satisfaction Guarantee! Please contact our customer service department for terms and conditions regarding the satisfaction guarantee.

How can I make such a bold guarantee? It's simple: I'm betting that once you start using it, you'll feel so good; you'll never want to be without it again.

But don't just take my word for it. Grab a no-risk supply of B12 Energy Booster* and see for yourself. You'll be glad you did.

Label Snapshot for Vitamin B12 Energy Booster* Spray
Supplement Facts
Serving Size: 6 Sprays (about 0.78 mL)
Servings Per Container: About 32       Amt. Per Serving     % Daily Value
Vitamin B12
(as Methylcobalamin)     1 mg     16,667%

OTHER INGREDIENTS: Water, Vegetable Glycerin, Natural Flavors, Citric Acid, Potassium Sorbate (to Maintain Freshness).

SUGGESTED USE: Adults, as a dietary supplement, shake before use, and take six (6) sprays daily.
View Complete Product Label
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Frequently Asked QuestionsFrequently Asked Questions
Top 5 Frequently Asked Questions

    1. Q: Why does Vitamin B12 Energy Booster* Spray contain methylcobalamin? Most of the B12 I see in stores is cyanocobalamin.

    A: Even though cyanocobalamin B12 appears to be the most popular form of B12 in supplements, I don't believe it's the most effective. Studies suggest that methylcobalamin:
        May be better utilized and retained in your body.*
        Is the active form of vitamin B12 and may have some applications not shared by other forms of the vitamin.*
        Is already in the active coenzyme form naturally found in your body and doesn't need to go through the conversion process.*    

    
    2. Q: Why is Vitamin B12 Energy Booster* not a capsule or tablet?

    A: Many people have difficulty swallowing pills. Vitamin B12 Energy Booster* Spray provides an easy and efficient way to get vitamin B12 since you simply spray it in your mouth.
    3. Q: How much vitamin B12 can I take in one day? Can I take too much?

    A: I recommend 6 sprays of my Vitamin B12 Energy Booster* Spray per day. However, there are no known side effects from taking more.
    4. Q: Can I take vitamin B12 at night or in the evening?

    A: If you experience sleep difficulties, try taking vitamin B12 during the day. B12 plays an important role in melatonin production.* As you age, your body becomes less efficient at producing enough melatonin, so taking B12 during the day can potentially support your melatonin production at night.*

    Every person is different. Some people find vitamin B12 energizes them at night if taken before bedtime while others find it helps them sleep.*
    5. Q: Where does vitamin B12's bright red color come from?

    A: Vitamin's bright red color comes from the mineral cobalt. Cobalt sits at the core of the B12 molecule, and is responsible for the other name B12 is often known as: cobalamin.

View Product Labels
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    Vitamin B12 Energy Booster* Spray
    Melatonin Sleep Support* Spray
    Vitamin D Spray
    Fermented Ginseng Spray



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Disclaimer: The entire contents of this website are based upon the opinions of Dr. Mercola, unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Mercola and his community. Dr. Mercola encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. If you are pregnant, nursing, taking medication, or have a medical condition, consult your health care professional before using products based on this content.

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